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5-Amino-1MQ
50 mg
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Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from adrenocorticotropic hormone, supplied as a 10mg lyophilized research peptide. It is studied for its effects on brain-derived neurotrophic factor (BDNF), neuroplasticity and cognitive processes.
Semax is a synthetic analogue of the ACTH(4-10) fragment of adrenocorticotropic hormone. It joins the ACTH(4-7) sequence, Met-Glu-His-Phe, to a Pro-Gly-Pro tripeptide that protects it from rapid enzymatic breakdown. The result keeps the neuroactive properties associated with ACTH fragments without the hormone's effect on the adrenal glands.
Semax was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences and was first described in the scientific literature in 1991. It is used as a prescription medicine in Russia, but it is not approved in Canada or the United States.
Much of the research on Semax centres on neurotrophic signalling. Brain-derived neurotrophic factor (BDNF) and its receptor TrkB support neuron survival, synaptic plasticity and learning, and Semax has been reported to increase their expression in the brain in animal models.
Other studies have examined its inhibition of the enzymes that break down enkephalins, the body's own opioid peptides.
In rats, Semax was reported to increase BDNF levels and TrkB receptor expression in the hippocampus, a brain region central to memory (Dolotov et al., Brain Research, 2006).
Semax and the related peptide Selank were also found to inhibit enkephalin-degrading enzymes in human serum (Kost et al., Russian Journal of Bioorganic Chemistry, 2001). This literature is cited for scientific context only.
Both are short Russian-developed peptides stabilised with a Pro-Gly-Pro tail. Semax is derived from the hormone ACTH and is studied mainly for neurotrophic and cognitive effects, while Selank is derived from the immune peptide tuftsin and is studied mainly in anxiety and stress-response research.
Semax is available as a 10mg lyophilized powder vial, shipped from Canada.
Store unopened vials in a cool, dry place away from direct light, with refrigeration recommended for long-term storage. After reconstitution, keep the vial refrigerated at 2–8°C.
Published literature is summarised for scientific context only. It is not a claim about this product, and this product is not for human or veterinary use.
Store unopened vials in a cool, dry environment away from direct light. For long-term storage, refrigeration is recommended. After reconstitution, keep refrigerated at 2–8°C and protect from direct light.
Not for human consumption. This product is sold exclusively as a research compound for in vitro and laboratory use by qualified researchers. It is not a drug, supplement, or cosmetic, is not intended for human or veterinary use, and is not intended to diagnose, treat, cure, or prevent any disease. No dosing, administration, or therapeutic claims are made or implied.
Published literature referenced on this page is provided for scientific context only and does not constitute a claim about this product or evidence of safety or efficacy in any organism.
By purchasing this product, you confirm that it will be used for legitimate research purposes in accordance with applicable laws and regulations.
