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5-Amino-1MQ
50 mg
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Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) based on the immune peptide tuftsin, supplied as a 10mg lyophilized research peptide. It is studied for its effects on stress responses, anxiety-related behaviour, monoamine signalling and BDNF expression.
Selank is a synthetic analogue of tuftsin, a four-amino-acid peptide (Thr-Lys-Pro-Arg) that occurs naturally as a fragment of immunoglobulin G and plays a role in immune function. Adding a Pro-Gly-Pro tail to the tuftsin sequence makes the peptide more stable against enzymatic breakdown.
It was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, the same institute that developed Semax. Selank is not approved in Canada or the United States.
Research on Selank has looked at both nervous-system and immune effects. Animal studies have reported changes in brain monoamine neurotransmitters such as serotonin and dopamine (Narkevich et al., 2008), changes in the expression of genes involved in GABAergic signalling (Volkova et al., Frontiers in Pharmacology, 2016) and changes in BDNF expression in the hippocampus.
Like Semax, Selank has also been found to inhibit enzymes that break down enkephalins, the body's own opioid peptides, which may contribute to its effects in stress and anxiety models. Its tuftsin origin has also led to research on cytokine and immune-cell responses.
In rats, intranasal Selank was reported to regulate BDNF expression in the hippocampus (Inozemtseva et al., Doklady Biological Sciences, 2008). Selank and Semax were both found to inhibit enkephalin-degrading enzymes in human serum (Kost et al., 2001).
Other studies have examined its effects on brain monoamine levels and on behaviour in rodent models of anxiety and depression. This literature is cited for scientific context only.
Selank is derived from the immune peptide tuftsin and is studied mainly in stress and anxiety research. Semax is derived from the hormone ACTH and is studied mainly for neurotrophic and cognitive effects. Both share a stabilising Pro-Gly-Pro tail.
Selank is available as a 10mg lyophilized powder vial, shipped from Canada.
Store unopened vials in a cool, dry place away from direct light, with refrigeration recommended for long-term storage. After reconstitution, keep the vial refrigerated at 2–8°C.
Published literature is summarised for scientific context only. It is not a claim about this product, and this product is not for human or veterinary use.
Store unopened vials in a cool, dry environment away from direct light. For long-term storage, refrigeration is recommended. After reconstitution, keep refrigerated at 2–8°C and protect from direct light.
Not for human consumption. This product is sold exclusively as a research compound for in vitro and laboratory use by qualified researchers. It is not a drug, supplement, or cosmetic, is not intended for human or veterinary use, and is not intended to diagnose, treat, cure, or prevent any disease. No dosing, administration, or therapeutic claims are made or implied.
Published literature referenced on this page is provided for scientific context only and does not constitute a claim about this product or evidence of safety or efficacy in any organism.
By purchasing this product, you confirm that it will be used for legitimate research purposes in accordance with applicable laws and regulations.
